PDZD8 contains a PDZ domain. PDZ domains are protein-interaction domains that are often found in multi-domain scaffolding proteins. The function of this protein remains unknown.
Function:
Plays a role in the regulation of cell morphology and cytoskeletal organization. May inhibit herpes simplex virus 1 infection at an early stage. May promote retroviral infection.
Subunit:
Interacts with MSN. Interacts with HISLV1 Gag polyprotein p55.
Similarity:
Contains 1 PDZ (DHR) domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
SWISS:
Q8NEN9
Gene ID:
118987
Database links:
Entrez Gene: 118987 Human
SwissProt: Q8NEN9 Human
Unigene: 501149 Human
Picture |
Sample:
Panc-1(Human) Cell Lysate at 30 ug
Primary: Anti-PDZD8 (SL9043R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 128 kD
Observed band size: 130kD
Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti-PDZD8 (SL9043R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 128 kD
Observed band size: 130 kD
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PDZD8 Polyclonal Antibody, Unconjugated (SL9043R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
|
|
|