Rabbit Anti-NKG2D antibody | Sunlong Medical

Home > Product > Antibody > Rabbit Anti-NKG2D antibody

KLRK1; natural killer cell group 2D; NKG2-D isoform b; Klrk1; Nkrp2; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NK cell receptor D; Killer cell lectin-like receptor subfamily K; NK lectin-like receptor; CD314; CD 314; CD314 a

Cat:

SL20660R

Species Reactivity：

Mouse,(predicted: Human,Rat,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human NKG2D:101-200/219<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000Flow-Cyt=1ug/Testnot yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lung (Mouse) Lysate at 40 ugRaw246.7(Mouse) Cell Lysate at 40 ugSpleen (Mouse) Lysate at 40 ugLymph node(Mouse) Lysate at 40 ugBone (Rat) Lysate at 40 ugPrimary: Anti- NKG2D (SL20660R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 25 kDObserved band size: 25 kDSample: Spleen (Mouse) Lysate at 40 ugPrimary: Anti-NKG2D(SL20660R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 25kDObserved band size: 26kDBlank control (blue line): Mouse thymus cells (fixed with 70% methanol (Overnight at 4℃) . Cells stained with Primary Antibody for 30 min at room temperature. The cells ). Primary Antibody (green line): Rabbit Anti-NKG2D antibody (SL20660R),Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE,Dilution: 1μg /test.

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This locus represents naturally occurring read-through transcription between the neighboring KLRC4 (killer cell lectin-like receptor subfamily C, member 4) and KLRK1 (killer cell lectin-like receptor subfamily K, member 1) genes on chromosome 12. The read-through transcript includes an alternate 5' exon and lacks a significant portion of the KLRC4 coding sequence, including the start codon, and it thus encodes the KLRK1 protein. [provided by RefSeq, Dec 2010]

Function:
Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

Subunit:
Homodimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).

Similarity:
Contains 1 SLCtype lectin domain.

SWISS:
P26718

Gene ID:
22914

Database links:

Entrez Gene: 22914 Human

Entrez Gene: 27007 Mouse

Entrez Gene: 24934 Rat

Omim: 611817 Human

SwissProt: P26718 Human

SwissProt: O54709 Mouse

SwissProt: O70215 Rat

Unigene: 387787 Human

Unigene: 8217 Mouse

Unigene: 14544 Rat

NKG2-D出现在免疫细胞上表达的受体，NKG2D属C型凝集素家族跨膜蛋白，广泛表达在NK细胞、CD8+的αβT细胞和γδT细胞表面，可以提高NK细胞对肿瘤细胞的杀伤活性。 Picture

Sample: Spleen (Mouse) Lysate at 40 ug
Primary: Anti-NKG2D(SL20660R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25kD
Observed band size: 26kD

Blank control (blue line): Mouse thymus cells (fixed with 70% methanol (Overnight at 4℃) . Cells stained with Primary Antibody for 30 min at room temperature. The cells ).
Primary Antibody (green line): Rabbit Anti-NKG2D antibody (SL20660R),Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE,Dilution: 1μg /test.

Product Feedback Wall