Home > Product > Antibody > Rabbit Anti-Peroxiredoxin-4 antibody
Antioxidant enzyme 372; Antioxidant enzyme AOE372; AOE37 2; AOE37-2; AOE372; EC 1.11.1.15; Peroxiredoxin IV; Peroxiredoxin-4; Peroxiredoxin4; PRDX 4; Prdx4; PRDX4_HUMAN; PRX 4; Prx IV; Prx-IV; PRX4; PrxIV; Thioredoxin dependent peroxide reductase A0372; T
Cat:
SL23510R
Species Reactivity:
Human,Mouse,(predicted: Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human Peroxiredoxin-4:31-130/271
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: K562(Human) Cell Lysate at 30 ugPrimary: Anti-Peroxiredoxin-4 (SL23510R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 27 kDObserved band size: 27 kDSample: Liver (Mouse) Lysate at 40 ugPrimary: Anti- Peroxiredoxin-4 (SL23510R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 27 kDObserved band size: 27 kDSample: Hela(Human) Cell Lysate at 30 ugPrimary: Anti-Peroxiredoxin-4  (SL23510R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 27 kDObserved band size: 27 kD
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Unit:
Price: $
Product PDFs
Datasheet:


The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]

Function:
Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

Subcellular Location:
Cytoplasm. Secreted.

Similarity:
Belongs to the ahpC/TSA family.
Contains 1 thioredoxin domain.

SWISS:
Q13162

Gene ID:
10549

Database links:

Entrez Gene: 281999 Cow

Entrez Gene: 10549 Human

Entrez Gene: 53381 Mouse

Entrez Gene: 85274 Rat

Omim: 606506 Human

SwissProt: Q9BGI2 Cow

SwissProt: Q13162 Human

SwissProt: O01767 Mouse

SwissProt: Q9Z0V5 Rat

Unigene: 83383 Human

Unigene: 247542 Mouse

Unigene: 17958 Rat



Picture

Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti-Peroxiredoxin-4 (SL23510R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- Peroxiredoxin-4 (SL23510R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti-Peroxiredoxin-4  (SL23510R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
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