Rabbit Anti-Synaptotagmin-4 antibody

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SYT4_HUMAN; Syt4; SytIV; HsT1192; KIAA1342; Synaptotagmin IV; SYT4; SYT 4; Syt IV; SytIV; Synaptotagmin4; SynaptotagminIV.

Cat:

SL1897R

Species Reactivity：

Human,Mouse,Rat,(predicted: Chicken,Dog,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human Synaptotagmin-4:301-400/425

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lane1:Brain(Mouse) Lysate at 30 ugLane2:Heart(Mouse) Lysate at 30 ugPrimary: Anti-SYNAPTOTAGMIN-4(SL1897R) at 1:200 dilution; Secondary: HRP conjugated Goat Anti-Rabbit IgG(SL0295G-HRP) at 1:3000 dilution; Predicted band size : 48kDObserved band size : 47kDSample: Cerebellum (Mouse) Lysate at 40 ugCerebrum (Rat) Lysate at 40 ugCerebral cortex (Mouse) Lysate at 40 ugHippocampus (Mouse) Lysate at 40 ugPrimary: Anti- Synaptotagmin-4 (SL1897R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 48 kDObserved band size: 50 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene belongs to the synaptotagmin family. Members of this family are multi-domained, integral membrane proteins of synaptic vesicles, and are thought to serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. This gene is primarily expressed in the nervous tissues. [provided by RefSeq].

Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.

Tissue Specificity:
Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.

Similarity:
Belongs to the synaptotagmin family.
Contains 2 C2 domains.

SWISS:
Q9H2B2

Gene ID:
6860

Database links:

Entrez Gene: 6860 Human

Omim: 600103 Human

SwissProt: Q9H2B2 Human

Unigene: 8059 Human

Picture

Sample:
Cerebellum (Mouse) Lysate at 40 ug
Cerebrum (Rat) Lysate at 40 ug
Cerebral cortex (Mouse) Lysate at 40 ug
Hippocampus (Mouse) Lysate at 40 ug
Primary: Anti- Synaptotagmin-4 (SL1897R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48 kD
Observed band size: 50 kD

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