Home > Product > Antibody > Rabbit Anti-CCR9 antibody
CCR-9; C C chemokine receptor D6; C C chemokine receptor type 9; C C CKR 9; CC Chemokine receptor CCR10; CC CKR 9; CCBP2; CCCKR9; CCR 9; CCR9; CDw199; CDw199 antigen; Chemokine C C motif receptor 9; Chemokine CC Motif Receptor 9; Chemokine receptor CCR 9;
Cat:
SL1788R
Species Reactivity:
Mouse,(predicted: Human,Rat,Dog,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human CCR9:65-160/369<Extracellular>
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: Thymus (Mouse) Lysate at 40 ugLymph node (Mouse) Lysate at 40 ugPrimary: Anti- CCR9 (SL1788R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 40 kDObserved band size: 48 kDCell: Mouse Spleen.Concentration:1:30. Incubation: 40 minutes. Host/Blank:Mouse Spleen Cells. Flow cytometric analysis of Rabbit Anti-CCR9 antibody (SL1788R)(green) compared with control in the absence of primary antibody (red) followed by mouse spleen cells.
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Unit:
Price: $
Product PDFs
Datasheet:


The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. Two alternatively spliced transcript variants have been described.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Highly expressed in the thymus and low in lymph nodes and spleen.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P51686

Gene ID:
10803

Database links:

Entrez Gene: 10803 Human

Entrez Gene: 12769 Mouse

Entrez Gene: 282832 Rat

Omim: 604738 Human

SwissProt: P51686 Human

SwissProt: Q9WUT7 Mouse

Unigene: 225946 Human

Unigene: 91140 Rat



Picture

Sample:
Thymus (Mouse) Lysate at 40 ug
Lymph node (Mouse) Lysate at 40 ug
Primary: Anti- CCR9 (SL1788R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 48 kD
Cell: Mouse Spleen.
Concentration:1:30.
Incubation: 40 minutes.
Host/Blank:Mouse Spleen Cells.
Flow cytometric analysis of Rabbit Anti-CCR9 antibody (SL1788R)(green) compared with control in the absence of primary antibody (red) followed by mouse spleen cells.
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