Rabbit Anti-TGF beta Receptor III antibody

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Beta glycan; TGF Beta R3; Betaglycan; Betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor B

Cat:

SL1910R

Species Reactivity：

Human,Mouse,Rat,(predicted: Chicken,Dog,Pig,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TGFBR3:701-850/850

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: K562 Cell (Human) Lysate at 40 ugHepG2 Cell (Human) Lysate at 40 ugHela Cell (Human) Lysate at 40 ugPrimary: Anti- TGF beta Receptor III (SL1910R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 94 kDObserved band size: 110 kDSample: Lane 1: Mouse Placenta tissue lysates Lane 2: Mouse Testis tissue lysates Lane 3: Rat Placenta tissue lysates Lane 4: Rat Testis tissue lysatesLane 5: Human HepG2 cell lysates Lane 6: Human HeLa cell lysates Lane 7: Human A431 cell lysates Primary: Anti-TGF beta Receptor III (SL1910R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 94 kDaObserved band size: 130 kDaIndependently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (SL1910R) at 1:250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining

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Unit:

Price: $220.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010].

Function:
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.

Subunit:
Interacts with TCTEX1D4.

Subcellular Location:
Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.

Post-translational modifications:
Extensively modified by glycosaminoglycan groups (GAG).

Similarity:
Contains 1 ZP domain.

SWISS:
Q03167

Gene ID:
7049

Database links:

Entrez Gene: 7049 Human

Entrez Gene: 21814 Mouse

Omim: 600742 Human

SwissProt: Q03167 Human

SwissProt: O88393 Mouse

Unigene: 482390 Human

Unigene: 200775 Mous

转化生长因子β受体Ⅲ，TGFβRⅢ Picture

Sample:
Lane 1: Mouse Placenta tissue lysates
Lane 2: Mouse Testis tissue lysates
Lane 3: Rat Placenta tissue lysates
Lane 4: Rat Testis tissue lysates
Lane 5: Human HepG2 cell lysates
Lane 6: Human HeLa cell lysates
Lane 7: Human A431 cell lysates
Primary: Anti-TGF beta Receptor III (SL1910R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 94 kDa
Observed band size: 130 kDa

Independently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (SL1910R) at 1:250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining

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