Rabbit Anti-IL17RB antibody

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IL17B Receptor; Interleukin-17 receptor B; IL17RB; IL-17RB; CRL 4; CRL4; Cytokine receptor CRL4; EVI 27; EVI27; IL 17 receptor B; IL 17 receptor homolog 1; IL 17B receptor; IL 17RB; IL 17Rh1; IL17BR; IL17RH1; Interleukin 17 receptor B; Interleukin 17 rece

Cat:

SL2610R

Species Reactivity：

Human,Mouse,Rat,(predicted: Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human IL-17RB:351-450/502<Cytoplasmic>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000Flow-Cyt=2μg /testnot yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lane 1: Rat Uterus tissue lysates Lane 2: Mouse Uterus tissue lysates Lane 3: Human A549 cell lysates Lane 4: Human HepG2 cell lysates Lane 5: Human HeLa cell lysates Lane 6: Human MCF-7 cell lysates Primary: Anti-IL17RB (SL2610R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 54 kDaObserved band size: 50 kDaSample: Liver (Mouse) Lysate at 40 ugPrimary: Anti-IL17RB (SL2610R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 54 kDObserved band size: 54 kDImage kindly submitted by Dr. Kang Chen from Wayne University via the Bioss Discovery Program.Positive staining with Human Peripheral Mononuclear Cells using Rabbit Anti-IL-17RB Polyclonal Antibody, ALEXA FLUOR 488 Conjugated (SL2610R-A488)

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Unit:

Price: $220.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq].

Function:
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.

Subunit:
Interacts with DAZAP2.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

Similarity:
Contains 1 SEFIR domain.

SWISS:
Q9NRM6

Gene ID:
55540

Database links:

Entrez Gene: 55540 Human

Omim: 605458 Human

SwissProt: Q9NRM6 Human

Unigene: 5470 Human

Picture

Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-IL17RB (SL2610R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD

Image kindly submitted by Dr. Kang Chen from Wayne University via the Bioss Discovery Program.Positive staining with Human Peripheral Mononuclear Cells using Rabbit Anti-IL-17RB Polyclonal Antibody, ALEXA FLUOR 488 Conjugated (SL2610R-A488)

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