Rabbit Anti-MARCO antibody | Sunlong Medical

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Macrophage receptor MARCO; Marco; MARCO_HUMAN; Macrophage receptor with collagenous structure; SCARA2; Scavenger receptor class A member 2.

Cat:

SL2659R

Species Reactivity：

Human,Mouse,Guinea Pig,(predicted: Rat,Chicken,Dog,)

Immunogen：

KLH conjugated synthetic peptide derived from human MARCO:421-520/520<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Tissue/cell: mouse lung tissue;4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min; Incubation: Anti-MARCO Polyclonal Antibody, Unconjugated(SL2659R-FITC) 1:100, overnight at 4°C; DAPI(5ug/ml,blue,SLC0033) was used to stain the cell nuclei

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Unit:

Price: $220.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, SLCterminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq].

Function:
Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria.

Subunit:
Homotrimer. Trimers may assemble in larger oligomers thus resulting in the creation of a large surface capable of interacting with very large ligands.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Similarity:
Contains 1 collagen-like domain.
Contains 1 SRCR domain.

SWISS:
Q9UEW3

Gene ID:
8685

Database links:

Entrez Gene: 8685 Human

Omim: 604870 Human

SwissProt: Q9UEW3 Human

Unigene: 67726 Human

Picture

Tissue/cell: mouse lung tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min;
Incubation: Anti-MARCO Polyclonal Antibody, Unconjugated(SL2659R-FITC) 1:100, overnight at 4°C; DAPI(5ug/ml,blue,SLC0033) was used to stain the cell nuclei

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