Rabbit Anti-MVD antibody | Sunlong Medical

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Diphosphomevalonate decarboxylase; FP17780; MDDase; Mevalonate (diphospho) decarboxylase; Mevalonate (diphospho)decarboxylase; Mevalonate pyrophosphate decarboxylase; MPD; Mvd; MVD1_HUMAN．

Cat:

SL5085R

Species Reactivity：

Mouse,Rat,(predicted: Human,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human MVD:201-300/400

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: H9C2(Rat) Cell Lysate at 30 ugHepG2(Human) Cell Lysate at 30 ugPrimary: Anti-MVD (SL5085R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 43 kDObserved band size: 43 kDParaformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MVD) Polyclonal Antibody, Unconjugated (SL5085R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The enzyme mevalonate pyrophosphate decarboxylase (MVD) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.

Function:
Performs the first committed step in the biosynthesis of isoprenes.

Subunit:
Homodimer.

Tissue Specificity:
Expressed in heart, skeletal muscle, lung,liver, brain, pancreas, kidney and placenta.

Similarity:
Belongs to the diphosphomevalonate decarboxylase family.

SWISS:
P5722

Gene ID:
4597

Database links:

Entrez Gene: 4597 Human

Entrez Gene: 192156 Mouse

Entrez Gene: 81726 Rat

Omim: 603236 Human

SwissProt: Q0P570 Cow

SwissProt: P5722 Human

SwissProt: Q99JF5 Mouse

SwissProt: Q62967 Rat

Unigene: 252457 Human

Unigene: 28146 Mouse

Unigene: 10288 Rat

Picture

Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MVD) Polyclonal Antibody, Unconjugated (SL5085R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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