Home > Product > Antibody > Rabbit Anti-ZnT-1 antibody
SLC30 A1; SLC30A 1; SLC30A1; Solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 (zinc transporter), member1; Solute carrier family 30 member 1; Solute carrier family 30, member 1; Zinc transporter 1; Zinc transporter1; ZNT 1;
Cat:
SL688R
Species Reactivity:
Human,Mouse,(predicted: Rat,Dog,Pig,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human ZnT-1:131-330/507
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample:Lovo cell (human) Lysate at 40 ugPrimary: Anti- ZnT-1(SL688R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 55kDObserved band size: 55kDSample:Large intestine (mouse) Lysate at 40 ugPrimary: Anti- ZnT-1(SL688R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 55kDObserved band size: 55kD
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Unit:
Price: $
Product PDFs
Datasheet:


Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a SLCterminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells.

Function:
May be involved in zinc transport out of the cell.

Subunit:
Multimer.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.

SWISS:
Q9Y6M5

Gene ID:
7779

Database links:

Entrez Gene: 7779 Human

Entrez Gene: 22782 Mouse

Entrez Gene: 58976 Rat

Omim: 609521 Human

SwissProt: Q9Y6M5 Human

SwissProt: Q60738 Mouse

SwissProt: Q62720 Rat

Unigene: 519469 Human

Unigene: 9024 Mouse

Unigene: 10120 Rat



Picture

Sample:Lovo cell (human) Lysate at 40 ug
Primary: Anti- ZnT-1(SL688R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55kD
Sample:Large intestine (mouse) Lysate at 40 ug
Primary: Anti- ZnT-1(SL688R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55kD
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