SLC30 A1; SLC30A 1; SLC30A1; Solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 (zinc transporter), member1; Solute carrier family 30 member 1; Solute carrier family 30, member 1; Zinc transporter 1; Zinc transporter1; ZNT 1;
Cat:
SL688R
Species Reactivity:
Human,Mouse,(predicted: Rat,Dog,Pig,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human ZnT-1:131-330/507
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample:Lovo cell (human) Lysate at 40 ugPrimary: Anti- ZnT-1(SL688R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 55kDObserved band size: 55kDSample:Large intestine (mouse) Lysate at 40 ugPrimary: Anti- ZnT-1(SL688R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 55kDObserved band size: 55kD
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a SLCterminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells.
Function: May be involved in zinc transport out of the cell.
Sample:Lovo cell (human) Lysate at 40 ug
Primary: Anti- ZnT-1(SL688R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55kD
Sample:Large intestine (mouse) Lysate at 40 ug
Primary: Anti- ZnT-1(SL688R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55kD
Product Feedback Wall
Specific References (1) | SL688R has been referenced in 1 publications.
[IF=6.543] Xiao Chuanpi. et al. High Temperature-Induced Oxidative Stress Affects Systemic Zinc Homeostasis in Broilers by Regulating Zinc Transporters and Metallothionein in the Liver and Jejunum. Oxid Med Cell Longev. 2022;2022:1427335 WB ; Broiler Chicks.