Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf43 gene product has been provisionally designated C9orf43 pending further characterization.
SWISS:
Q8TAL5
Gene ID:
257169
Database links:
Entrez Gene: 257169 Human
SwissProt: Q8TAL5 Human
Unigene: 632691 Human
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Sample:
Placenta(Mouse) Lysate at 40 ug
Primary: Anti-C9ORF43 (SL9493R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Sample:
B16 (Mouse) Cell Lysate at 40 ug
Primary: Anti-C9ORF43 (SL9493R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
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