This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]
Subcellular Location:
Endoplasmic reticulum membrane. Microsome membrane.
Tissue Specificity:
Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.
Similarity:
Belongs to the cytochrome P450 family.
SWISS:
Q86W10
Gene ID:
199974
Database links:
Entrez Gene: 199974 Human
SwissProt: Q86W10 Human
Unigene: 176588 Human
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Sample: HT29(Human) Cell Lysate at 40 ug
Primary: Anti-CYP4Z1(SL14163R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 59kD
Observed band size: 59kD
Sample: HepG2 (Human)Cell Lysate at 40 ug
Primary: Anti-CYP4Z1(SL14163R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 59kD
Observed band size: 59kD
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