C20orf108 is a 192 amino acid multi-pass membrane protein that contains one DUF1279 domain. C20orf108 is encoded by a gene located on human chromosome 20q13.2. Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought to be important for seminal production. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf108 gene product has been provisionally designated C20orf108 pending further characterization.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the FAM210 family.
Contains 1 DUF1279 domain.
SWISS:
Q96KR6
Gene ID:
116151
Database links:
Entrez Gene: 116151 Human
SwissProt: Q96KR6 Human
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Protein: lung(rat) lysates at 30ug;
Primary: Anti-FAM210B (SL14887R) at 1:200;
Secondary: HRP conjugated Goat Anti-Rabbit IgG(SL0295G-HRP) at 1: 3000;
ECL excitated the fluorescence;
Predicted band size : 20kD
Observed band size : 20kD
Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min;
Incubation: Anti-FAM210B Polyclonal Antibody, Unconjugated(SL14887R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(SLC0010) staining
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