Rabbit Anti-LARP7 antibody | Sunlong Medical

Home > Product > Antibody > Rabbit Anti-LARP7 antibody

DKFZp564K112; HDCMA18P; La related protein 7; La ribonucleoprotein domain family member 7; La ribonucleoprotein domain family member 7; La-related protein 7; LARP 7; larp7; LARP7_HUMAN; MGC104360; P TEFb interaction protein for 7SK stability; P

Cat:

SL17106R

Species Reactivity：

Mouse,(predicted: Human,Rat,Chicken,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human LARP7:501-582/582

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Paraformaldehyde-fixed, paraffin embedded (mouse testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LARP7) Polyclonal Antibody, Unconjugated (SL17106R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LARP7) Polyclonal Antibody, Unconjugated (SL17106R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Function:
Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Subcellular Location:
Nucleus > nucleoplasm.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 HTH La-type RNA-binding domain.
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q4G0J3

Gene ID:
51574

Database links:

Entrez Gene: 51574 Human

Entrez Gene: 28036 Mouse

Entrez Gene: 686883 Rat

Omim: 612026 Human

SwissProt: Q4G0J3 Human

SwissProt: Q05CL8 Mouse

SwissProt: Q5XI01 Rat

Unigene: 713663 Human

Unigene: 291032 Mouse

Unigene: 168323 Rat

Picture

Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LARP7) Polyclonal Antibody, Unconjugated (SL17106R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

Product Feedback Wall