Rabbit Anti-MAGT1 antibody | Sunlong Medical

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bA217H1; DKFZp564K142; FLJ14726; IAG2; IAP; Implantation-associated protein; Magnesium transporter 1; MagT1; MGC64926; MRX95; Oligosaccharyltransferase 3 homolog B; OST3B; OTTHUMP00000023589; OTTHUMP00000062081; PRO0756; RP11-217H1.1.

Cat:

SL18633R

Species Reactivity：

Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MAGT1:101-200/335

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAGT1) Polyclonal Antibody, Unconjugated (SL18633R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (rat stomach tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAGT1) Polyclonal Antibody, Unconjugated (SL18633R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010]

Function:
May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg2+ transport in epithelial cells.

Subunit:
Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B

Subcellular Location:
Cell membrane.

Tissue Specificity:
Ubiquitous. Expressed at very low levels in brain, lung and kidney.

DISEASE:
Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia (XMEN) [MIM:300853]: A disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T-lymphocyte activation.
Note: The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the OST3/OST6 family.
Contains 1 thioredoxin domain.

SWISS:
Q9H0U3

Gene ID:
300715

Database links:

Entrez Gene: 16861 Human

Entrez Gene: 67075 Mouse

Entrez Gene: 116967 Rat

Omim: 300715 Human

SwissProt: Q9H0U3 Human

SwissProt: Q9CQY5 Mouse

SwissProt: O35777 Rat

Unigene: 323562 Human

Picture

Paraformaldehyde-fixed, paraffin embedded (rat stomach tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAGT1) Polyclonal Antibody, Unconjugated (SL18633R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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