is gene (IFNGR1) encodes the ligand-binding chain(alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq].
Subcellular Location: Membrane; Single-pass type I membrane protein.
Similarity: Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. Contains 2 Ig-like C2-type (immunoglobulin-like)domains.
SWISS: P15261
Gene ID: 15979
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Sample:
HepG2 (Human) Cell Lysate at 30 ug
Hela (Human) Cell Lysate at 30 ug
Primary: Anti- IFNGR1 (SL21607R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 50 kD
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti-IFNGR1 (SL21607R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
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Specific References (1) | SL21607R has been referenced in 1 publications.
[IF=4.237] Tomokazu Ohnishi. et al. Ultraviolet B irradiation decreases CXCL10 expression in keratinocytes through endoplasmic reticulum stress. 2021 Apr 28 WB ; Human.