Rabbit Anti-Defensin beta 2 antibody

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beta-defensin 2 precursor; beta Defensin 2; beta-defensin 2; Defb2; Q32ZI5_RAT; DFB4A_HUMAN.Defensin β2.

Cat:

SL1296R

Species Reactivity：

Human,(predicted: Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from rat beta 2 Defensin:21-71/71

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min; Incubation: Anti-beta 2 Defensin Polyclonal Antibody, Unconjugated(SL1296R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(SLC0010) staining

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Unit:

Price: $220.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the skin and respiratory tract.

Similarity:
Belongs to the beta-defensin family. LAP/TAP subfamily.

SWISS:
Q32ZI5

Gene ID:
641631

Database links:

防御素在人体中广泛分布的，目前已知的α－防御素有6种，研究人员从人体的肾脏、气管、鼻粘膜与唾液中也发现了两种β防御素，在许多器官的上皮细胞与非上皮组织的细胞中发现了β－防御素。
Defensin β2在维持肌体天然免疫功能、介导炎症反应以及调节特异性免疫中的作用引起人们的重视，防御素的表达与病原体的入侵紧密相关。 Picture

Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min;
Incubation: Anti-beta 2 Defensin Polyclonal Antibody, Unconjugated(SL1296R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(SLC0010) staining

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