Rabbit Anti-KLF13 antibody | Sunlong Medical

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Basic transcription element binding protein 3; BTE binding protein 3; BTEB3; C2 H2 zinc finger protein; FKLF 2; FKLF2; Kruppel like factor 13; Novel Sp1 like zinc finger transcription factor; NSLP1; RANTES factor of late activated T lymphocytes 1; RFLAT-1

Cat:

SL1577R

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human KLF13:197-249/288

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min; Incubation: Anti-KLF13 Polyclonal Antibody, Unconjugated(SL1577R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(SLC0010) staining

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Kruppel-like factor 13 (KLF13) belongs to a family of transcription factors that contain three classical zinc finger DNA binding domains consisting of a zinc atom tetrahedrally coordinated by two cysteines and two histidines (C2H2 motif). These transcription factors bind to GC rich sequences and related GT and CACCC boxes. KLF13 appears to be an important component of the transcription network required for heart development and cholesterol homeostasis.

Function:
Represses transcription by binding to the BTE site, a GSLCrich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.

SWISS:
Q9Y2Y9

Gene ID:
51621

Database links:

Entrez Gene: 51621 Human

Entrez Gene: 50794 Mouse

Omim: 605328 Human

SwissProt: Q9Y2Y9 Human

SwissProt: Q9JJZ6 Mouse

Unigene: 525752 Human

Unigene: 48473 Mouse

Picture

Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,SLC0005) at 37℃ for 20 min;
Incubation: Anti-KLF13 Polyclonal Antibody, Unconjugated(SL1577R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(SLC0010) staining

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