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Home > Product > Antibody > Rabbit Anti-IL20 antibody
Interleukin-20; four alpha helix cytokine; IL10D; Interleukin 20; Interleukin-20; ZCYTO10; IL20_MOUSE; Cytokine Zcyto10; IL-20; IL20_HUMAN; MGC96907; UNQ852/PRO1801.
Cat:
SL1834R
Species Reactivity：
Rat,(predicted: Human,Mouse,)
Immunogen：
KLH conjugated synthetic peptide derived from mouse IL-20:51-150/176
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (rat skin tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-20) Polyclonal Antibody, Unconjugated (SL1834R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Unit:
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Product PDFs
Datasheet:


IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.

Function:
Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed at very low levels in skin, trachea, and other tissues.

Similarity:
Belongs to the IL-10 family.

SWISS:
Q9JKV9

Gene ID:
58181

Database links:

Entrez Gene: 50604 Human

Entrez Gene: 58181 Mouse

SwissProt: Q9NYY1 Human

SwissProt: Q9JKV9 Mouse



白介素20是新发现的细胞因子，属于白介素10家族成员。它可由活化的外周血单一核细胞和角质形成细胞产生。与其他白介素10家族成员的受体亚单位有交叉反应，多用于银屑病及风湿病的研究。 Picture

Paraformaldehyde-fixed, paraffin embedded (rat skin tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-20) Polyclonal Antibody, Unconjugated (SL1834R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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