Rabbit Anti-IL5RA antibody | Sunlong Medical

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Interleukin-5 receptor alpha; CD125 antigen; CDw125; HSIL5R3; IL5R; IL-5R; Interleukin 5 Receptor alpha; Interleukin 5 receptor subunit alpha; interleukin 5 receptor type 3; MGC26560; IL5RA; IL-5R alpha; IL5RA_HUMAN.

Cat:

SL2601R

Species Reactivity：

Human,Mouse,(predicted: Rat,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human IL-5R alpha:11-110/420<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: testis (mouse) Lysate at 40 uglung (mouse) Lysate at 40 ugovary (mouse) Lysate at 40 ugA549 (human)cell Lysate at 40 ugPrimary: Anti- IL5RA(SL2061R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 46kDObserved band size: 56 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Function:
This is the receptor for interleukin-5. The alpha chain binds to IL5.

Subunit:
Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with SDCBP.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed on eosinophils and basophils.

Similarity:
Belongs to the type I cytokine receptor family. Type 5 subfamily.

SWISS:
Q01344

Gene ID:
3568

Database links:

Entrez Gene: 3568 Human

Entrez Gene: 16192 Mouse

Omim: 147851 Human

SwissProt: Q01344 Human

SwissProt: P21183 Mouse

Unigene: 207105 Human

Unigene: 68876 Human

Unigene: 3448 Mouse

Picture

Sample:
testis (mouse) Lysate at 40 ug
lung (mouse) Lysate at 40 ug
ovary (mouse) Lysate at 40 ug
A549 (human)cell Lysate at 40 ug
Primary: Anti- IL5RA(SL2061R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46kD
Observed band size: 56 kD

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