Rabbit Anti-IL10RB antibody

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Cd210; CDw210b; CRF2 4; CRF2-4; CRFB4; Cytokine receptor class II; Cytokine receptor class II CRF2 4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; Cytokine receptor family II member 4; D21S58; D21S66; I10R2_HUMAN; IL-10 recept

Cat:

SL2602R

Species Reactivity：

Human,Mouse,Rat,(predicted: Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human IL-10RB:21-120/325<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: HepG2(Human) Cell Lysate at 30 ugLung (Mouse) Lysate at 40 ugLung (Rat) Lysate at 40 ugPrimary: Anti-IL10RB (SL2602R) at 1/200 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 39 kDObserved band size: 39 kDSample: Lane 1: Spleen (Rat) Lysate at 40 ugLane 2: Lung (Rat) Lysate at 40 ugLane 3: Small intestine (Rat) Lysate at 40 ugLane 4: Lymph node (Rat) Lysate at 40 ugPrimary: Anti-IL10RB (SL2602R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 37 kDObserved band size: 33 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Interleukin 10 binds specifically and with high affinity to cell surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. Mouse and human cDNA clones encoding the ligand binding IL10 receptor have been isolated. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10.

Subcellular Location:
Membrane; Single-pass type I membrane

Similarity:
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.

SWISS:
Q08334

Gene ID:
3588

Database links:

Entrez Gene: 3588 Human

Entrez Gene: 16155 Mouse

Entrez Gene: 304091 Rat

Omim: 123889 Human

SwissProt: Q08334 Human

SwissProt: Q61190 Mouse

Unigene: 654593 Human

Unigene: 4154 Mouse

Picture

Sample:
Lane 1: Spleen (Rat) Lysate at 40 ug
Lane 2: Lung (Rat) Lysate at 40 ug
Lane 3: Small intestine (Rat) Lysate at 40 ug
Lane 4: Lymph node (Rat) Lysate at 40 ug
Primary:
Anti-IL10RB (SL2602R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 33 kD

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