Killer cell immunoglobulin-like receptor 2DS4; CD158 antigen like family member I; CD158I; CD158i antigen; CL 17; CL 39; CL17; CL39; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 4; Killer inhibitory receptor 4 1 2; KIR antig
Cat:
SL2644R
Species Reactivity：
Human,
Immunogen：
KLH conjugated synthetic peptide derived from human CD158i:221-290/290
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: HL-60 Cell (Human) Lysate at 30 ugPrimary: Anti-KIR2DS4'CD158i (SL2644R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 31 kDObserved band size: 48 kD
The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family. KIR2DS4 is a receptor on natural killer (NK) cells for HLA C alleles. It does not inhibit the activity of NK cells.
Function: Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Subcellular Location: Cell membrane; Single-pass type I membrane protein.
Similarity: Belongs to the immunoglobulin superfamily. Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Sample:
HL-60 Cell (Human) Lysate at 30 ug
Primary: Anti-KIR2DS4'CD158i (SL2644R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kD
Observed band size: 48 kD
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Specific References (1) | SL2644R has been referenced in 1 publications.
[IF=2.38] Mozer-Lisewska, Iwona, et al. "Detection and Significance of Cytotoxic Cell Subsets in Biopsies of HCSLVInfected Human Livers." Archivum immunologiae et therapiae experimentalis (2013): 1-8. Human.
