[email protected]
Home > Product > Antibody > Rabbit Anti-SOD3 antibody
EC-SOD; Superoxide Dismutase 3; ALS; ALS1; Cu/Zn superoxide dismutase; EC SOD; Extracellular superoxide dismutase [Cu Zn]; Extracellular superoxide dismutase; Extracellular superoxide dismutase precursor; Homodimer; Indophenoloxidase A; IPOA; Mn superoxid
Cat:
SL3895R
Species Reactivity：
Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human SOD3:227-240/240
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: Placenta (Mouse) Lysate at 40 ugPrimary: Anti-SOD3(SL3895R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 24kDObserved band size: 27kD
More
prev next
Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the SLCterminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]

Function:
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.

Subunit:
Homotetramer.

Subcellular Location:
Secreted, extracellular space. Note=99% of ESLCSOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.

Tissue Specificity:
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.

Similarity:
Belongs to the Cu-Zn superoxide dismutase family.

SWISS:
P08294

Gene ID:
6649

Database links:

Entrez Gene: 6649 Human

Entrez Gene: 20657 Mouse

Entrez Gene: 25352 Rat

Omim: 185490 Human

SwissProt: P08294 Human

SwissProt: O09164 Mouse

SwissProt: Q08420 Rat

Unigene: 2420 Human

Unigene: 487 Mouse

Unigene: 10358 Rat



Picture

Sample: Placenta (Mouse) Lysate at 40 ug
Primary: Anti-SOD3(SL3895R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24kD
Observed band size: 27kD
Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.