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Home > Product > Antibody > Rabbit Anti-PFKFB1 antibody
6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 1; 6-bisphosphatase; 6-P2ase 1; 6-P2ASE liver isozyme; 6PF 2 K/Fru 2 6 P2ASE liver isozyme; 6PF 2 K/Fru 2,6 P2ase 1; 6PF-2-K/Fru-2; F261_HUMAN; F6PK; Fructose 2 6 bisphosphatase; Fructose 6 phosphate 2 k
Cat:
SL5004R
Species Reactivity：
Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human PFKFB1:21-120/471
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (mouse liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PFKFB1) Polyclonal Antibody, Unconjugated (SL5004R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Unit:
Price: $
Product PDFs
Datasheet:


PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.

Function:
Synthesis and degradation of fructose 2,6-bisphosphate.

Subunit:
Homodimer.

Tissue Specificity:
Liver.

Similarity:
In the SLCterminal section; belongs to the phosphoglycerate mutase family.

SWISS:
P16118

Gene ID:
5207

Database links:

Entrez Gene: 5207 Human

Entrez Gene: 18639 Mouse

Entrez Gene: 117276 Rat

SwissProt: P16118 Human



Picture

Paraformaldehyde-fixed, paraffin embedded (mouse liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PFKFB1) Polyclonal Antibody, Unconjugated (SL5004R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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