Rabbit Anti-TRPC6 antibody | Sunlong Medical

Home > Product > Antibody > Rabbit Anti-TRPC6 antibody

MTRP6; Short transient receptor potential channel 6; si:rp71-1p14.9; Transient Receptor Potential Cation Channel Subfamily C Member 6; Transient receptor protein 6; TRP 6; TRP-6; TRP6; TRPC 6; TrpC6; TRPC6_HUMAN; TRRP6; bZ1P14.9; FLJ11098; FLJ14863; FSGS2

Cat:

SL2393R

Species Reactivity：

Human,Mouse,Rat,(predicted: Dog,Pig,Cow,Horse,Rabbit,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRPC6:651-750/931<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500Flow-Cyt=0.2μg/Test（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

blank control(blue): U937 cells (fixed with 4% paraformaldehyde)Isotype control(orange): Cell lines treated with rabbit IgG (SL0295P)instead of the primary antibody to confirm that primary antibody binding is specific. primary antibody(Green):Rabbit Anti-CD162 antibody(SL2301R),Concebtration: 0.2μg/10^6 cells Secondary only control(light blue): Both cell lines treated with Goat Anti-rabbit IgG/FITC antibody (SL0295G-FITC) to confirm no background signal produced from secondary antibody alone.

prev next

Unit:

Price: $220.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq].

Subunit:
Interacts with MX1 and RNF24.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.

Similarity:
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily.
Contains 4 ANK repeats.

SWISS:
Q9Y210

Gene ID:
7225

Database links:

Entrez Gene: 7225 Human

Entrez Gene: 22068 Mouse

Entrez Gene: 89823 Rat

Omim: 603652 Human

SwissProt: Q9Y210 Human

SwissProt: Q61143 Mouse

Unigene: 159003 Human

Unigene: 325086 Mouse

Unigene: 105986 Rat

Picture

blank control(blue): U937 cells (fixed with 4% paraformaldehyde)
Isotype control(orange): Cell lines treated with rabbit IgG (SL0295P)instead of the primary antibody to confirm that primary antibody binding is specific. primary antibody(Green):Rabbit Anti-CD162 antibody(SL2301R),Concebtration: 0.2μg/10^6 cells
Secondary only control(light blue): Both cell lines treated with Goat Anti-rabbit IgG/FITC antibody (SL0295G-FITC) to confirm no background signal produced from secondary antibody alone.

Product Feedback Wall