This enzyme condenses acetyl CoA with acetoacetyl CoA to form HMG CoA, which is the substrate for HMG CoA reductase.
Function:
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the HMG-CoA synthase family.
SWISS:
Q01581
Gene ID:
3157
Database links:
Entrez Gene: 3157 Human
Entrez Gene: 100040592 Mouse
Entrez Gene: 208715 Mouse
Entrez Gene: 29637 Rat
Omim: 142940 Human
SwissProt: Q01581 Human
SwissProt: Q8JZK9 Mouse
SwissProt: P17425 Rat
Unigene: 397729 Human
Unigene: 61526 Mouse
Unigene: 5106 Rat
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Sample:
Kidney (Mouse) Lysate at 40 ug
Liver (Mouse) Lysate at 40 ug
Primary: Anti-HMGCS1(SL5069R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57kD
Observed band size: 57kD
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