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Home > Product > Antibody > Rabbit Anti-SPINK1 antibody
ISK1_HUMAN; Serine protease inhibitor Kazal-type 1; Pancreatic secretory trypsin inhibitor; PCTT; PSTI; TCP; TATI; Serine protease inhibitor Kazal type 1; Spink 3; Spink3; Tumor-associated trypsin inhibitor (TATI);
Cat:
SL2916R
Species Reactivity：
Human,
Immunogen：
KLH conjugated synthetic peptide derived from human SPINK1:31-79/79
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SPINK1) Polyclonal Antibody, Unconjugated (SL2916R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Unit:
Price: $
Product PDFs
Datasheet:


The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]

Function:
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.

Subcellular Location:
Secreted.

Similarity:
Contains 1 Kazal-like domain.

SWISS:
P00995

Gene ID:
6690

Database links:

Entrez Gene: 6690 Human

SwissProt: P00995 Human



Picture

Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SPINK1) Polyclonal Antibody, Unconjugated (SL2916R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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