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Home > Product > Antibody > Rabbit Anti-Fetuin A/AHSG antibody
Fetuin-A; 59 kDa bone sialic acid containing protein; A2HS; Aa2 066; AHS; AHSG; Alpha 2 HS glycoprotein; Alpha 2 HS glycoprotein chain A; Alpha 2 Z globulin; Alpha 2HS glycoprotein; alpha2 Heremans Schmid glycoprotein; Asialofetuin; Ba alpha 2 glycoprotei
Cat:
SL2922R
Species Reactivity：
Human,(predicted: Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human Alpha-2-HS-glycoprotein chain A.:201-300/367
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: liver (mouse)cell Lysate at 40 ugPrimary: Anti- Fetuin A/AHSG (SL2922R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 31kDObserved band size: 34 kD
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Product PDFs
Datasheet:


Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008]

Function:
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

Subunit:
Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond.

Subcellular Location:
Secreted.

Tissue Specificity:
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

Similarity:
Belongs to the fetuin family.
Contains 2 cystatin fetuin-A-type domains.

SWISS:
P02765

Gene ID:
197

Database links:

Entrez Gene: 197 Human

Entrez Gene: 26998 Human

Omim: 138136 Human

Omim: 605954 Human

SwissProt: P02765 Human

SwissProt: Q9UGM5 Human

Unigene: 324746 Human

Unigene: 81073 Human



Picture

Sample: liver (mouse)cell Lysate at 40 ug
Primary: Anti- Fetuin A/AHSG (SL2922R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31kD
Observed band size: 34 kD
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