A2MRAP; A2RAP; Alpha 2 macroglobulin receptor associated protein; Alpha 2 MRAP; HBP44; Lipoprotein receptor associated protein; Low density lipoprotein receptor related protein associated protein 1; Low density lipoprotein related protein associated prote
Cat:
SL6055R
Species Reactivity：
Human,(predicted: Mouse,Rat,Pig,)
Immunogen：
KLH conjugated synthetic peptide derived from human LRPAP1/MRAP:131-330/357
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: Hela (Human) Cell Lysate at 30 ug293T (Human) Cell Lysate at 30 ugPrimary: Anti- LRPAP1 (SL6055R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 38 kDObserved band size: 38 kD
A2MRAP;
A2RAP;
Alpha 2 macroglobulin receptor associated protein;
Alpha 2 MRAP;
HBP44;
Lipoprotein receptor associated protein;
Low density lipoprotein receptor related protein associated protein 1;
Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein;
Low density lipoprotein related protein associated protein 1;
LRPAP1;
MRAP;
RAP.
Function: Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
Subunit: Present on cell surface forming a complex with the alpha-2-macroglobulin receptor heavy and light chains. Binds LRP1B; binding is followed by internalization and degradation.
Subcellular Location: Endoplasmic reticulum. Cytoplasm. Cell surface. Note=Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.
Post-translational modifications: N-glycosylated.
DISEASE: Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
Sample:
Hela (Human) Cell Lysate at 30 ug
293T (Human) Cell Lysate at 30 ug
Primary: Anti- LRPAP1 (SL6055R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 38 kD
