Isoform 5 and isoform 6 are highly expressed in the brain. Both isoforms derive from naturally occurring readthrough transcripts which produce IQCJ-SCHIP1 fusion proteins.
Subcellular Location:
Cytoplasm. Partially colocalizes with NF2 beneath the cytoplasmic membrane.
Similarity:
Contains 1 IQ domain.
SWISS:
Q1A5X6
Gene ID:
654502
Database links:
Entrez Gene: 654502 Human
Omim: 611622 Human
SwissProt: Q1A5X6 Human
Unigene: 570685 Human
Picture |
Paraformaldehyde-fixed, paraffin embedded (human pancreatic carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IQCJ) Polyclonal Antibody, Unconjugated (SL6102R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
|
|
|