Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response
Function:
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
xpressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney.
Similarity:
Belongs to the Niban family.
SWISS:
Q9BZQ8
Gene ID:
116496
Database links:
Entrez Gene: 116496 Human
SwissProt: Q9BZQ8 Human
Unigene: 518662 Human
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Sample:
HL-60(Human) Cell Lysate at 30 ug
Primary: Anti- FAM129A (SL6534R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 103 kD
Observed band size: 103 kD
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