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Home > Product > Antibody > Rabbit Anti-Upstream Binding Protein 1 antibody
LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.
Cat:
SL6730R
Species Reactivity：
Mouse,(predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse,)
Immunogen：
KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1:351-450/540
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: Pancreas (Mouse) Lysate at 40 ugPrimary: Anti- Upstream Binding Protein 1 (SL6730R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 60 kDObserved band size: 56 kD
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Product PDFs
Datasheet:


Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HISLV1 initiation site and weakly over the TATA-box. Represses HISLV1 transcription by inhibiting the binding of TFIID to the TATA-box.

Function:
UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.

Subunit:
Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

Similarity:
Belongs to the grh/CP2 family. CP2 subfamily.

SWISS:
Q9NZI7

Gene ID:
7342

Database links:

Entrez Gene: 7342 Human

Entrez Gene: 22221 Mouse

Entrez Gene: 301038 Rat

Omim: 609784 Human

SwissProt: Q86Y57 Human

SwissProt: Q9NZI7 Human

SwissProt: Q60786 Mouse

SwissProt: Q811S7 Mouse

SwissProt: Q8SH21 Mouse

Unigene: 23641 Human

Unigene: 729120 Human

Unigene: 28052 Mouse

Unigene: 381368 Mouse

Unigene: 15705 Rat



Picture

Sample:
Pancreas (Mouse) Lysate at 40 ug
Primary: Anti- Upstream Binding Protein 1 (SL6730R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 56 kD
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