KLH conjugated synthetic peptide derived from human WSB2/WD SOCS box protein 2:51-150/404
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: U251 (Human) Cell Lysate at 30 ugSiha (Human) Cell Lysate at 30 ugPrimary: Anti-WD SOCS box protein 2 SL6752R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 45 kDObserved band size: 45 kD
WSB2 is a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the SLCterminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases.
Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Sample:
U251 (Human) Cell Lysate at 30 ug
Siha (Human) Cell Lysate at 30 ug
Primary: Anti-WD SOCS box protein 2 SL6752R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 45 kD