Home > Product > Antibody > Rabbit Anti-Granzyme K antibody
Fragmentin 3; Fragmentin-3; Fragmentin3; GRAK_HUMAN; Granzyme 3; Granzyme K; Granzyme K precursor; Granzyme-3; Granzyme3; GranzymeK; GZMK; NK TRYP 2; NK TRYP2; NK tryptase 2; NK-TRYP-2; NK-tryptase-2; NKTRYP2; Serine protease granzyme 3; TRYP 2; TRYP2; Tr
Cat:
SL6788R
Species Reactivity:
Mouse,(predicted: Human,Rat,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human Granzyme K:51-250/264
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: Spleen (Mouse) Lysate at 40 ugPrimary: Anti-Granzyme K (SL6788R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 26 kDObserved band size: 26 kD
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Unit:
Price: $
Product PDFs
Datasheet:


This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008].

Subcellular Location:
Secreted. Cytoplasmic granule.

Tissue Specificity:
Expressed in lung, spleen, thymus and peripheral blood leukocytes.

Similarity:
Belongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain.

SWISS:
P49863

Gene ID:
3003

Database links:

Entrez Gene: 3003 Human

Entrez Gene: 14945 Mouse

Entrez Gene: 29165 Rat

Omim: 600784 Human

SwissProt: P49863 Human

SwissProt: O35205 Mouse

SwissProt: P49864 Rat

Unigene: 277937 Human

Unigene: 56993 Mouse

Unigene: 11190 Rat



Picture

Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti-Granzyme K (SL6788R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD
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