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GA2L1_HUMAN; GAR 22; GAR22; GAS2 like protein 1; GAS2 related protein on chromosome 22; GAS2-like protein 1; GAS2-related protein on chromosome 22; GAS2L1; Growth arrest specific 2 like 1; Growth arrest specific protein 2 like 1; Growth arrest-specific pr
Cat:
SL6836R
Species Reactivity：
Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from Human GAS2L1:201-300/681
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GAS2L1) Polyclonal Antibody, Unconjugated (SL6836R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Product PDFs
Datasheet:


The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
Seems to be involved in the cross-linking of microtubules and microfilaments.

Subcellular Location:
Cytoplasm, cytoskeleton (Probable).

Similarity:
Belongs to the GAS2 family.
Contains 1 CH (calponin-homology) domain.
Contains 1 GAR domain.

SWISS:
Q99501

Gene ID:
10634

Database links:

Entrez Gene: 518935 Cow

Entrez Gene: 10634 Human

Entrez Gene: 78926 Mouse

Entrez Gene: 72973 Rat

Omim: 602128 Human

SwissProt: Q99501 Human

SwissProt: Q8JZP9 Mouse

Unigene: 322852 Human

Unigene: 374836 Mouse

Unigene: 44591 Mouse

Unigene: 22169 Rat



Picture

Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GAS2L1) Polyclonal Antibody, Unconjugated (SL6836R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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