Rabbit Anti-ZNF420 antibody

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APAK; ATM and p53 associated KZNF protein; FLJ32191; Zinc finger protein 420; ZNF 420; ZN420_HUMAN.

Cat:

SL7092R

Species Reactivity：

Mouse,(predicted: Human,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF420:301-688/688

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Paraformaldehyde-fixed, paraffin embedded (mouse placenta); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZNF420) Polyclonal Antibody, Unconjugated (SL7092R) at 1:5000 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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ZNF420 contains 19 C2H2-type zinc fingers and 1 KRAB domain. It may be involved in transcriptional regulation. It is a negative regulator of p53-mediated apoptosis.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus (Potential).

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 19 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
Q8TAQ5

Gene ID:
147923

Database links:
UniProtKB/Swiss-Prot: Q8TAQ5.1

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