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Home > Product > Antibody > Rabbit Anti-FAM161B antibody
C14orf44; Chromosome 14 open reading frame 44; Family with sequence similarity 161, member B; FLJ31697; Hypothetical protein LOC145483; Protein FAM161B; F161B_HUMAN.
Cat:
SL8226R
Species Reactivity：
Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,)
Immunogen：
KLH conjugated synthetic peptide derived from human FAM161B:451-560/647
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM161B) Polyclonal Antibody, Unconjugated (SL8226R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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Unit:
Price: $
Product PDFs
Datasheet:


FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.

Subunit:
Interacts with FAM161A.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the FAM161 family.

SWISS:
Q96MY7

Gene ID:
145483

Database links:
UniProtKB/Swiss-Prot: Q96MY7.2

Picture

Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAM161B) Polyclonal Antibody, Unconjugated (SL8226R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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