Class II histocompatibility antigen M alpha chain; D6S222E; DMA; HLA class II histocompatibility antigen DM alpha chain; HLA DMA; HLADM; Major histocompatibility complex class II DM alpha; MHC class II antigen DMA; Really interesting new gene 6 protein; R
Cat:
SL6968R
Species Reactivity：
Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,)
Immunogen：
KLH conjugated synthetic peptide derived from human HLA DM:101-200/261
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: Lung (Mouse) Lysate at 40 ugPrimary: Anti-HLA DM (SL6968R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 26 kDObserved band size: 26 kD
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. HLA DM plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.
Subunit: Heterodimer of an alpha chain (DMA) and a beta chain (DMB).
Subcellular Location: Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.
Similarity: Belongs to the MHC class II family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
SWISS: P28067
Gene ID: 3108
Database links: UniProtKB/Swiss-Prot: P28067.1
Picture
Sample: Lung (Mouse) Lysate at 40 ug
Primary: Anti-HLA DM (SL6968R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD
