chromosome 18 open reading frame 1; clone 22; LRAD4_HUMAN; LDLRAD4; Low Density Lipoprotein Receptor Class A Domain Containing 4; Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 4.
Cat:
SL9652R
Species Reactivity:
Human,(predicted: Mouse,Rat,Cow,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human C18orf1:6-100/306<Extracellular>
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: A549 Cell (Human) Lysate at 40 ugPrimary: Anti-C18orf1 (SL9652R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 34 kDObserved band size: 36 kD
C18orf1 is a 306 amino acid single-pass membrane protein that contains one LDL-receptor class A domain and belongs to the PMEPA1 family. C18orf1 exists as five alternatively spliced isoforms that display selective expression and are encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
Subcellular Location: Cell membrane; Single-pass membrane protein (Potential).
Tissue Specificity: Expressed in lymphocytes.
Similarity: Belongs to the PMEPA1 family. Contains 1 LDL-receptor class A domain.