Rabbit Anti-CD32 antibody | Sunlong Medical

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CD32B; FCGR2B; IGFR2; Lym 1; CD32 antigen; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, recept

Cat:

SL4991R

Species Reactivity：

Human,

Immunogen：

KLH conjugated synthetic peptide derived from human CD32:101-200/310<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: U937(Human) Cell Lysate at 30 ugPrimary: Anti-CD32 (SL4991R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 31 kDObserved band size: 33 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Function:
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

Subunit:
Isoform IIB1 interacts with measles virus N protein. N protein is released in the blood following lysis of measles infected cells. This interaction presumably block inflammatory immune response. Interacts with INPP5D/SHIP1. Interacts with FGR. Interacts with LYN.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.

Post-translational modifications:
Phosphorylated by SRSLCtype Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.

Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
P31994

Gene ID:
2213

Database links:

Entrez Gene: 2213 Human

SwissProt: P31994 Human

Picture

Sample:
U937(Human) Cell Lysate at 30 ug
Primary: Anti-CD32 (SL4991R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kD
Observed band size: 33 kD

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