GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two SLCterminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.
Subunit:
Interacts with PRKX.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the MOS2 family.
Contains 1 G-patch domain.
Contains 2 KOW domains.
SWISS:
Q92917
Gene ID:
27238
Database links:
Entrez Gene: 102116765 Cynomolgus monkey
Entrez Gene: 101127648 Gorilla
Entrez Gene: 27238 Human
Entrez Gene: 100461351 Orangutan
SwissProt: Q92917 Human
Unigene: 503666 Human
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Sample:
A431(Human) Cell Lysate at 30 ug
Primary: Anti- GPKOW (SL8577R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
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