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Home > Product > Antibody > Rabbit Anti-FABP3/H-FABP antibody
MDGI; FABP11; H-FABP; M-FABP; O-FABP; Fatty acid-binding protein, heart; Fatty Fatty acid-binding protein 3; Heart-type fatty acid-binding protein (H-FABP); Mammary-derived growth inhibitor (MDGI); Muscle fatty acid-binding protein (M-FABP); FABPH_HUMAN;
Cat:
SL11283R
Species Reactivity：
Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human FABP3:8-100/133
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Cardiac FABP) Polyclonal Antibody, Unconjugated (SL11283R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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Unit:
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Product PDFs
Datasheet:


Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). MDGI is highly expressed in the myocardium, skeletal and smooth muscle fibers, lipid and/or steroid synthesizing cells and terminally differentiated epithelia of the respiratory, intestinal and urogenital tracts.

Function:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

SWISS:
P05413

Gene ID:
2170

Database links:

Entrez Gene: 2170 Human

Entrez Gene: 14077 Mouse

Entrez Gene: 79131 Rat

SwissProt: P05413 Human

SwissProt: P11404 Mouse

SwissProt: P07483 Rat



Picture

Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Cardiac FABP) Polyclonal Antibody, Unconjugated (SL11283R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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