GPR89A is a nearly identical copy of the GPR89B gene (MIM62566).
Function:
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.
Subunit:
Homotrimer.
Subcellular Location:
Golgi apparatus membrane; Multi-pass membrane protein.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the Golgi pH regulator (TC 1.A.38) family.
SWISS:
B7ZAQ6
Gene ID:
653519
Database links:
Entrez Gene: 653519 Human
Entrez Gene: 67549 Mouse
Entrez Gene: 362003 Rat
Omim: 612821 Human
SwissProt: B7ZAQ6 Human
SwissProt: Q8BS95 Mouse
Picture |
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GPR89A) Polyclonal Antibody, Unconjugated (SL15391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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