KLH conjugated synthetic peptide derived from human HERPUD2:21-120/406
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: HL-60 Cell (Human) Lysate at 40 ugK562 Cell (Human) Lysate at 40 ugPrimary: Anti- HERPUD2 (SL15465R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 45 kDObserved band size: 50 kD
The endoplasmic reticulum (ER) stress response is triggered by the accumulation of unfolded proteins within the ER and is characterized by three events: the inhibition of translation (to prevent further protein accumulation), the up-regulated expression of polypeptide-folding proteins (known as the unfolded protein response or UPR) and the degradation of misfolded proteins by the ER-associated protein degradation (ERAD) system. Members of the homocysteine-inducible and ER stress-inducible ubiquitin-like domain families are components of the ERAD system and, via their ubiquitin-like domain, are thought to be involved in the destruction of misfolded proteins. HERPUD2 (Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2) is a 406 amino acid single-pass membrane protein containing one N-terminal ubiquitin-like domain. HERPUD2 is thought to be involved in the unfolded protein response (UPR) pathway.
Function: Could be involved in the unfolded protein response (UPR) pathway (By similarity).
Subcellular Location: Membrane; Single-pass membrane protein (Potential).
Sample:
HL-60 Cell (Human) Lysate at 40 ug
K562 Cell (Human) Lysate at 40 ug
Primary: Anti- HERPUD2 (SL15465R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 50 kD