IFIT1L is a 474 amino acid protein that belongs to the IFIT family and contains eight TPR repeats. The gene encoding IFIT1L maps to human chromosome 10q23.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Similarity:
Belongs to the IFIT family.
Contains 8 TPR repeats.
SWISS:
Q5T764
Gene ID:
439996
Database links:
Entrez Gene: 439996 Human
SwissProt: Q5T764 Human
Unigene: 500491 Human
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Paraformaldehyde-fixed, paraffin embedded (Human gastric cance); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFIT1B ) Polyclonal Antibody, Unconjugated (SL15554R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (sp-0023) for 20 minutes and DAB staining.
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