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Home > Product > Antibody > Rabbit Anti-FIAA antibody
F1A alpha; FEM1B_HUMAN; Fem 1 like in apoptotic pathway protein alpha; FEM-1 homolog b; FEM-1-like death receptor binding protein; FEM1 beta; FIAA; Protein FEM 1 homolog b.
Cat:
SL14677R
Species Reactivity：
Mouse,Rat,(predicted: Human,Cow,Horse,)
Immunogen：
KLH conjugated synthetic peptide derived from human FIAA:1-100/627
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FIAA) Polyclonal Antibody, Unconjugated (SL14677R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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Product PDFs
Datasheet:


This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013]

Subcellular Location:
Cytoplasm. Nucleus. Note: In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin.

Tissue Specificity:
Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.

Similarity:
Belongs to the fem-1 family.
Contains 8 ANK repeats.
Contains 1 TPR repeat.

SWISS:
Q9UK73

Gene ID:
10116

Database links:

Entrez Gene: 10116 Human

Entrez Gene: 415559 Chicken

Entrez Gene: 14155 Mouse

Entrez Gene: 315745 Rat

Omim: 613539 Human

SwissProt: Q5ZM55 Chicken

SwissProt: Q9UK73 Human

SwissProt: Q9Z2G0 Mouse

SwissProt: P0C6P7 Rat

Unigene: 362733 Human



Picture

Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FIAA) Polyclonal Antibody, Unconjugated (SL14677R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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