[email protected]
Home > Product > Antibody > Rabbit Anti-FA83D antibody
2310007D09Rik; BB104611; C20orf129; CHICA; dJ616B8.3; FA83D_HUMAN; FAM83D; Family with sequence similarity 83, member D; FLJ38341; MGC92947; Protein FAM83D; RGD1565583; RP23-119H5.1; Spindle protein CHICA.
Cat:
SL14678R
Species Reactivity：
Rat,(predicted: Human,Mouse,Dog,Pig,Horse,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human FA83D:151-225/225
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FA83D) Polyclonal Antibody, Unconjugated (SL14678R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
More
prev next
Unit:
Price: $
Product PDFs
Datasheet:


Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis which are thought important for seminal production and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The FAM83D gene product has been provisionally designated FAM83D pending further characterization.

Function:
Required for proper chromosome congression and alignment during mitosis. Required for targeting KIF22/KID to the spindle microtubules.

Subcellular Location:
Cytoplasm. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Primarily cytoplasmic during interphase, but beginning in prophase, associates with spindle microtubules, with a clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase.

Similarity:
Belongs to the FAM83 family.

SWISS:
Q9H4H8

Gene ID:
81610

Database links:

Entrez Gene: 81610 Human

SwissProt: Q9H4H8 Human

Unigene: 726442 Human



Picture

Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FA83D) Polyclonal Antibody, Unconjugated (SL14678R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.