FAM194B is a 696 amino acid protein that belongs to the FAM194 family and is alternatively spliced created two isoforms. The gene encoding FAM194B maps to human chromosome 13, which comprises nearly 4% of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival.
Function:
The function of this protein remains unknown.
Similarity:
Belongs to the FAM194 family.
SWISS:
Q7L0X2
Gene ID:
131831
Database links:
Entrez Gene: 131831 Human
SwissProt: Q7L0X2 Human
Unigene: 147128 Human
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Sample:
293T(Human) Cell Lysate at 30 ug
Primary: Anti-FAM194B (SL14774R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 82 kD
Observed band size: 82 kD
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