GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]
Function:
Orphan receptor.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
O95800
Gene ID:
10936
Database links:
Entrez Gene: 10936 Human
Entrez Gene: 237716 Mouse
Omim: 606704 Human
SwissProt: O95800 Human
SwissProt: Q6X632 Mouse
Unigene: 40763 Human
Unigene: 338361 Mouse
Unigene: 484157 Mouse
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Sample:
Cerebrum (Mouse)Lysate at 40 ug
Heart (Mouse)Lysate at 40 ug
Primary: Anti-GPCR GPR75(SL16263R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 59kD
Observed band size: 54kD
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