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Home > Product > Antibody > Rabbit Anti-TIMM23 antibody
MGC22767; MGC93478; Mitochondrial import inner membrane translocase subunit Tim23; Predicted protein of HQ1197; PRO1197; TIM23; TIM23_HUMAN; TIM-23; TIMM 23; TIMM23; Translocase of inner mitochondrial membrane 23 (yeast) homolog; Translocase of
Cat:
SL7375R
Species Reactivity：
Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human TIMM23:111-209/209
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TIMM23) Polyclonal Antibody, Unconjugated (SL7375R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Product PDFs
Datasheet:


TIMM23 nomenclature and NM_006327.2 were associated with GeneID:10431 in build 37.1. Because of assembly problems in this region, it was later determined that GeneID:100287932 correctly represents the location of TIMM23. TIMM23 is now associated with GeneID:100287932 and NM_006327.2. [17 Mar 2010]

Function:
TIMM23 belongs to the Tim17/Tim22/Tim23 family and is an essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Subunit:
Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM50. The complex interacts with the TIMM44 component of the PAM complex and with DNAJC15.

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

Similarity:
Belongs to the Tim17/Tim22/Tim23 family.

SWISS:
O14925

Gene ID:
10431

Database links:

Entrez Gene: 10431 Human

Omim: 605034 Human

SwissProt: O14925 Human



Picture

Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TIMM23) Polyclonal Antibody, Unconjugated (SL7375R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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